Further research from human trials would be necessary to further investigate this issue, and strong claims are currently unwarranted. It happens when old bone mass removal is not compensated by new bone mass addition. Your bones are made of a protein matrix, and your body mineralizes this matrix with calcium, magnesium, and phosphorus to make strong healthy bones that do not break easily. For these reasons, researchers believe that testing serum levels of osteocalcin may be a useful screening option for assessing osteoporosis (bone loss) risk (15). Interestingly, this MK-7 supplementation resulted in significant reductions in the calcification of the patients’ blood vessels (36). Anyhow there are some of the delusions that our body can convert K1 to K2, animals can convert K1 to K2, but humans need food containing K2 or … Image via Pixabay . Osteocalcin plays a vital role in strengthening bones, and one of its primary functions is to bind calcium and take it to the bone (13, 14). Final thoughts. Vitamin K2 could help maintain youthful skin activating Matrix-GLA and in turn preventing calcification of elastin. Vitamin K1 (phytonadione) and vitamin K2 (menaquinone) are available in North America. Vitamin K 2 or menaquinone (/ ˌ m ɛ n ə ˈ k w ɪ n oʊ n /) is one of three types of vitamin K, the other two being vitamin K 1 (phylloquinone) and K 3 . Vitamins D and K2 have a synergistic effect in some areas. I am 71. Known as the “forgotten vitamin”, scientists and researchers have only started studying vitamin K2 in the last two decades for its newly found benefits despite having a long history of use. Keeps Blood Clotting Normally For more information on Dr. Lin’s clinical protocol that highlights the steps parents can take to prevent dental problems in their children: Click here. As skin ages, it loses both collagen and elastin, and its youthful appearance along with them. Calcification heralds heart disease. Your email address will not be published. In addition to protecting your heart, vitamin K2 supports healthy circulation and benefits blood clotting. It’s mostly responsible for the dental health and osteoporosis prevention-based benefits of vitamin. Vitamin K2 Benefits. People with polymorphisms for matrix-GLA protein also have higher risk of kidney stones. US Barnes & Noble Intake of vitamin K2 may have importance for human health as the vitamin appears to have a host of beneficial functions in the body. Inadequate K2 inhibits osteocalcin production and … That's one reason why we've created our own Vitamin D supplement. ?I It stops bleeding by making the blood clot and contributes to cardiovascular and bone health. Varicose veins are not always detrimental to our health but can be unsightly and uncomfortable. Vitamin K2 is linked to calcium metabolism. Vitamin K2 is a form of the fat-soluble vitamin K that is found in organ meats and fermented foods. Additionally, research also showed that higher vitamin K2 intake was associated with a reduced risk of fatal cancer. This potent apoptotic effect was observed on human bladder cancer cells but NOT on normal cells. “Vitamin K2 as MK-7 is the only compound to date shown to impact arterial calcification through its activation of MGP, which is why it is garnering attention from the medical community as a potential therapy,” says Christopher Speed, Senior Vice President of Global Sales and Marketing with NattoPharma, the world leaders in vitamin K2 research and development. Weaving the ancient principles of ancient TCM (Traditional Chinese Method) with body-ready vitamin K2 and superfood ingredients, Ancient Nutrients Vitamin K2 features a potent combination of bone-supporting real-food ingredients with body-ready vitamin K2. In artery and heart cells, if calcium levels are too high within a cell, the cell actually changes physically and will die. 3 Major Benefits of Vitamin K2. Statins inhibit the synthesis of vitamin K2, the cofactor for matrix Gla-protein activation, which in turn protects arteries from calcification. Compared to the placebo group, the women treated with vitamin D, K and calcium saw a beneficial, greater decrease in testosterone and other hormone levels (31). Osteocalcin is a necessary protein that helps maintain calcium homeostasis in bone tissue. Brief history of vitamin K2 Benefits of vitamin K2 Vitamin K2 and its role in hormone production could both prevent and help treat polycystic ovary syndrome. Low testosterone in men is considered a factor in some age-related diseases. I’ve personally dissolved visible bone spurs in my finger and wrist joints with an uptake of K2; so it can’t hurt. I wonder if K2 would help to slow down or remove these. It’s known to have actions in the kidney, and lungs too. The process is called carboxylation. While children and adolescents require vitamin K2 for bone development to ensure healthy physical growth, adults aged 60 and older around the globe are leading more active lifestyles and taking on greater responsibility for their health. Another form of this vitamin, K1 or phylloquinone, is used for: Vitamin K2 and Calcium (CAC) Score; oubobcat @oubobcat. Osteocalcin depends on vitamin K2 for activation via carboxylation (11). I think MK4 is the last essential nutrient to be discovered. Once again, this association was not present for vitamin K1 (17). Commenting on the relationship between MK4 and insulin resistance, my own experience is that MK4 simply doesn’t work if you have serious insulin resistance–all you get is side-effects! Each one in this group is distinguished by a number, such as MK7 or MK4. Here are some of the ways in which vitamin K2 may have benefits. However, recently, Vitamin K2-dependent proteins have been shown to play a key role in the brain and central and peripheral nervous systems. From what I understand you can’t over-do it, as the body gets rid of excess. There are many different forms of vitamin K2, but the two primary forms found in food are: On the other hand, vitamin K1 (phylloquinone) mainly occurs in plant foods, predominantly in dark green vegetables such as collard greens and spinach. Vitamin K2 benefits. Vitamin K1 10 mg daily and vitamin K2 45 mg daily have been safely used for up to 2 years. Deficiency in it gives Vitamin D3 no alternative but to splash Calcium all over the walls of Arteries and Veins. Vitamin K2 also reduced the inflammation markers in the body in such cases. An exploration of ancestral medicine, the human microbiome and epigenetics it’s a complete guide to the mouth-body connection. ... One of vitamin K2’s functions is to stimulate the protein osteocalcin which funnel’s calcium out from the bloodstream and into appropriate areas of the body such as the bone and teeth. The half-life of MK-7 in the blood is much longer, but on the other hand, that means the tissues take up MK-4 really quickly when it’s available, which could also be looked at in a positive way. When it breaks down calcium in our bodies, vitamin K2 activates a protein that helps the mineral bind to our bones to … Vitamin K2 Activates a Protein for proper Blood Clotting slowing possible hemorrhaging or bleeding. Canada INDIGO. It’s worth investing a little time and effort to get more of this superstar if you’re looking for something to give that competitive edge. Vitamin K2 seems to be in the spotlight lately, and for good reason. Vitamin K2 has an advantage over K1 because it is likely absorbed better than K1, which is poorly absorbed from its plant food sources [3,4]. They may even have an antioxidant role in the brain itself. Vitamin D is a fat-soluble vitamin that affects every cell within our body, and calcium is a vital mineral for skeletal health, amongst other things. Notably, in a recent pre-post intervention clinical trial, chronic kidney disease (CKD) patients with vitamin K deficiency underwent four weeks of supplementation with menaquinone-7. In other words, it is when the body makes less bone mass or loses bone mass, or both. One of the major benefits of vitamin K2 is that it activates osteocalcin, which is a protein hormone made by the bones. The protein that triggers builds bones and depositing calcium in bones is called Osteocalcin. Studies show that K2 supplementation leads to higher levels of osteocalcin in the blood (12). Read on to learn the benefits, side effects and food sources of vitamin K2. Because osteocalcin is a K2-dependent protein, increasing vitamin K2 intake causes osteocalcin to work more efficiently. Benefits of vitamin K2 Management of Osteoporosis. Builds New Dentin. Benefits of Vitamin K2. Vitamin K2 activated matrix Gla protein is also needed to protect the cartilage in the growth plates of the bones from prematurely calcifying. As we’ve discussed in this series, the benefits of Vitamin K2 begin from inside your teeth, right through to your gums, heart and bones. Vitamin K2 deficiency is a major cause of kidney stones. Most supplements I’ve seen are around 100ug. Also known as menaquinone, Vitamin K2 is associated with several health benefits and cardiovascular benefits. Ongoing research has confirmed that vitamin K2’s role in human health extends beyond what’s possible with K1. Healthy skin . When it comes to vitamin K2 side effects, you need to learn about the basics of vitamin K2 first. Not only letting teeth be spoiled and waiting for cash… That’s good! The blood lipid profile was also improved. Last Updated on July 2, 2020 by Michael Joseph. A Danish scientist named Henrik Dam made the discovery of the vitamin K group of vitamins in 1929 (1). Have you suffered from any condition related to Vitamin K2? However, there are numerous educated assumptions that we can make. For example, initial research from the Heidelberg cohort of the European prospective investigation into cancer and nutrition (EPIC-Heidelberg) study suggested there might be an inverse association between menaquinone (particularly from dairy) and prostate cancer (17). So increasing RBCs with Iron and B12 (+) D3 and K2 for proper calcium absorption made Raynaud’s go away for me. A lesser source is vitamin K2, or menaquinone, which occurs in some animal-based and fermented foods. How to Check for Normal Tongue vs. Tongue Tie, Vitamin D Through Sun: 9 Tips to Optimize Your Levels. And a specific kind of vitamin K2 known as MK-7 outshines all the other formulations of vitamin K in helping people grow stronger bones by removing calcium for plaques in the linings of arteries. Natural Vitamin K2-7 is very important for healthy life e.g. It is important in libido, bone density, sperm production, and building muscle. K 2 is both a tissue and bacterial product (derived from vitamin K 1 in both cases) and is usually found in animal products or fermented foods. As skin ages, it loses both collagen and elastin, and its youthful appearance along with them. Vitamin K2 is the name for a group of substances that are also known as MKs or menaquinones. Take the journey and the 40-day delicious food program for life-changing oral and whole health. Healthier Bones. Vitamin K2 MK-7 benefits consumers of all ages, life-stages and gender. Its role could be key in the neuro-degenerative process. One risk factor for kidney stones is excess Vitamin D, as demonstrated in lifeguards. 1. The most important benefits of vitamin K2 supplements include the following: Improve bone health. per meal and it only took a couple of days to make my teeth feel so much better!… Read more », I wanted to add to my comments on the connection between MK4 and insulin resistance. my wife’s vision has improved since she started taking k2 mk4 and mk-7. Vitamin K2 has been studied for the last 80+ years and known to be a critical nutrient. In short; a greater intake of vitamin K2 may improve insulin sensitivity, but the evidence for this effect is unclear, and more research is necessary. Vitamin K is a fat-soluble vitamin that is known to be involved in blood clotting, and to have importance for bone health. Some people get painful calcium deposits on their tendons. Pseudoxanthoma elasticum: A condition where the mineralization of skin and premature wrinkles occur. Given the way vitamin K2 works, there might be a mechanism there, but I don’t really know to be honest. Additionally, chronic kidney disease patients typically have a subclinical vitamin K deficiency, suggesting that this group may benefit from a greater intake of the vitamin (38). Studies in rats have showed that a diet providing MK-4 75 mg/kg enhanced testosterone levels compared to the control. From its role in strengthening the skeletal system to protecting against arterial calcification, the vitamin seemingly has numerous powerful functions. First of all, vitamin K1 has very poor bioavailability, and studies show that K1 absorption may be as low as 4% in foods like spinach (39). See this article for more information on the best food sources of vitamin K2 (and an overview of the differences between MK-4 and MK-7). Vitamin K2 Benefits. A little-used supplement called vitamin K2 offers enormous benefits for both cardiovascular and bone health. An adequate dietary intake of vitamin K2 may potentially be protective against certain forms of cancer. When doctors and dentists discuss the benefits of vitamin K, they are often referring to the health benefits of vitamin K1, which the NIH describes as the preferred form of the vitamin. A meta-analysis of existing studies supports the link between vitamin K2 and improved bone health. Matrix-GLA protein has a role in preventing stroke due to its cardiovascular benefits. T … While vitamin K2 was not always known as a nutrient for bone health, its importance is now recognized. Let me tell you about vitamin K2 benefits. Posts: 1 Joined: Apr 06, 2019. Required fields are marked *. I think between 100-200 ug daily is ok. Synergia Life Sciences brings the most valuable bioactive natural agents. In addition, a randomized trial featuring 379 healthy men and women demonstrated that individuals with poor vitamin K status had higher concentrations of the pro-inflammatory cytokines CRP and interleukin-6 (IL6) (27). You also find K2 in animal products like fatty fish and grass-fed beef, or in fermented foods like natto. NutritionAdvance.com does not provide medical advice. Talk to a Dr. Berg Keto Consultant today and get the help you need on your journey. Without enough vitamin K, blood clotting can be inhibited, increasing the risk for excessive blood loss upon injury. For example, vitamin D appears to promote the production of Vitamin-K dependent bone proteins (24). Vitamin K2 induced mitochondria-related apoptosis in human bladder cancer cells via ROS-JNK/p38 MAPK signal pathways. Anyhow there are some of the delusions that our body can convert K1 to K2, animals can convert K1 to K2, but humans need food containing K2 or … That said, it can only have these benefits if it goes to the right place, and this is where vitamin K comes in. One of the major benefits of vitamin K2 is that it activates osteocalcin, which is a protein hormone made by the bones. Interestingly, a large observational study of 4807 participants found that those consuming the highest amounts of vitamin K2 had the lowest risk of developing cardiovascular heart disease (7). Testosterone is a hormone present in greater quantities in men than women. Health Benefits of Vitamin K2 1. Since Vitamin K plays an essential role in blood clotting and research has shown it is important for bone health, let’s take a closer look at the health benefits of Vitamin K2. However ! Both forms of vitamin K are vital to your body’s blood clotting process — though K2 may be better at it. Additionally, the Rotterdam Study showed that menaquinone (K2) decreased the risk of arterial calcification and cardiovascular disease mortality. Most of the research has focused on vitamin K1 and its effects associated with blood coagulation. Vitamin K2 – (or menaquinone) is a more absorbable form of Vitamin K found in certain fermented foods and supplements is used by soft tissues and is helpful for bones, heart tissue and more Vitamin K3 – (or menadione) is a synthetic form of Vitamin K. People with chronic kidney disease and those receiving dialysis are at risk of Vitamin K deficiency. Vitamin K2 Health Benefits. This hormonal imbalance includes the over-production of testosterone (29, 30). Any recommendation on the use of K2 also? While vitamin D is more widely recognized for its supplemental benefits, vitamin K2 is a largely underrated vitamin, but it’s finally starting to get the attention it deserves. As a supplement, vitamin K2 may help with osteoporosis, heart disease, inflammation, and more. You can see the top 7 health benefits of vitamin K2 below: Please note: The benefits below are true of all forms of vitamin K2. Vitamin K has two main forms: vitamin K1 and vitamin K2. Vitamin K2 Benefits and Side Effects . Furthermore, a randomized controlled trial featuring 78 women over the age of 60 found that the combination of vitamin K, D, and calcium improved bone mineral density over six months (25). If it is an issue for someone you know, this might be something worth discussing with a doctor/specialist. It is certainly important as it supplements the functions of calcium and vitamin D, as noted by a study published in the Journal of Nutrition and Metabolism. Our bodies need calcium to build and maintain bones. Collagen and elastin are two of the components of skin that give it firmness and elasticity. Heart Disease. Additionally, researchers consider the protein to have a reparative role in the dental pulp (22). How much of K-2 to take daily? Posted by oubobcat @oubobcat, Apr 6, 2019 . The Linus Pauling Institute notes that while vitamins K-1 and K-2 are nontoxic, vitamin K-3 can be toxic, which is why it is no longer used to treat vitamin K deficiency 1. Benefits of Vitamin K2. That is an interesting point… perhaps this could suggest that MK-4 plays some sort of protective role in the liver? If you get a cut, vitamin K1 helps your blood cells and platelets aggregate near a wound to form a clot so you don’t bleed to death. Firstly, a placebo-controlled trial found that four weeks of vitamin K2 supplementation improved insulin sensitivity in young men, potentially through the activation of osteocalcin (32). Vitamin K2 is found in the fermented grass and other fermented foods because K2 is a product of fermentation. Recent research has found that maintaining a sufficient intake of vitamin K2 may help to improve insulin sensitivity. K2 is in animal proteins and fermented foods. On this note, research shows that osteocalcin is found in inflamed pulpal tissues, suggesting that it may play a regenerative role. I’m sure that has helped but I also started to take K2. What is Vitamin K2? Great stress test. Vitamin K2 activates two key proteins in the body. Although vitamin K has been around for decades, dietary recommendations have been overshadowed by the nominal amount of K1 required for healthy blood clotting—and have ignored the optimal amounts of vitamin K2 needed to maintain healthy bones and arteries at all stage of life. Vitamin K2 is also needed by the infant to support skeletal development both during gestation and after birth. Ongoing research has confirmed that vitamin K2’s role in human health extends beyond what’s possible with K1. It was also postulated that vitamin K2 could reduce insulin resistance and the risk of type 2 … Want to know more? She was using 3.5 on her reading glasses and now she doesn’t need them. This article examines the differences between the two, as well as their sources and benefits. I like the idea that MK4 and MK7 can have different (but equally beneficial) effects in the body. © 2018 Dr Steven Lin. Vitamin K2. This fat-soluble vitamin also promotes brain function and fights chronic diseases. Some of these “consequences” include vascular calcifications, bleeding, and higher mortality (37). A vitamin that can unlock heart disease by reversing it and preventing it … we’re breaking down Vitamin K2 today! Osteocalcin depends on vitamin K2 for activation via carboxylation ( 11 ). Vitamin K has a range of structures with "K1; phylloquinone" and "K2; menaquinone" being the first major difference. You also find K2 in animal products like fatty fish and grass-fed beef, or in fermented foods like natto. This cartilage is … It is stronger, less toxic and faster acting. Vitamin K2 supplements are safe, and there have been no reported side effects, even at high doses. Vitamin K2 may have another key benefit through potentially lowering markers of inflammation within the body. Is Vitamin D a Cure for Snoring and Sleep Apnea? While this discovery came in the early 20th century, the beneficial effects of vitamin K2 are only recently coming to light (2). Its main role is to control clotting. UK AMAZON Vitamin K2 Benefits That Will Improve Your Health . For your body to absorb the health benefits of Vitamin K2, you need fat-soluble Vitamin A and Vitamin D . Vitamin K2 is a form of vitamin K, which is an essential vitamin. Also consider D3, Iron, and B12. Vitamin K2 is Different from Vitamin K1 Vitamin K1, also known as phylloquinone, is found in leafy greens, like spinach, collard, broccoli. Australia BOOKTOPIA Recently, however, research has begun to demonstrate that vitamin K1 is likely more involved in blood clotting than is vitamin K2. Although the precise absorption rate of vitamin K2 is not known, the consumption of menaquinone-7 significantly raises serum vitamin K levels. It works with osteoblast cells to build healthy bone tissue. Reducing inflammation in the body also reduces the risk of type 2 diabetes. Thanks for majestic information. 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